Friendly Reminder: We love sharing wellness tips, but supplements aren’t one-size-fits-all. Check with your doctor before adding anything new to your routine. Mushrooms are powerful. They can interact with medications such as blood thinners, immune therapies, or diabetes medications.

If you’ve been wandering through our Whole Health aisle lately, you may have noticed a growing number of mushroom supplements sitting proudly on the shelves. They’re not the button mushrooms you toss in your stir-fry—these are the heavy hitters of the fungi world, long treasured in traditional medicine and now making a splash in wellness circles right here in Oregon and beyond.
So, what’s the deal with mushroom supplements? Let’s forage.
Why Mushrooms?
Mushrooms are more than just tasty umami bombs—they’re loaded with compounds like beta-glucans, antioxidants, and adaptogens that support everything from immunity to mental clarity. Pacific Northwest companies like Host Defense (founded by Olympia’s Paul Stamets, one of the world’s leading mycologists) and Oregon’s own wellness makers have helped put mushroom supplements on the map, crafting tinctures, capsules, and powders from responsibly grown fungi.
Meet the Mushroom All-Stars
Lion’s Mane: The Brain Booster

What it’s good for: Focus, memory, and supporting nerve health.
How it’s used: Often taken as a capsule or mixed into coffee powder blends.
Local love: Host Defense Lion’s Mane is a local favorite—made right up the road in Washington. Many folks say it helps with mental clarity or brain fog. You may also like Oregon-made, Microjoy Elevate. These delicious gummies blend the best of Lion’s Mane with L-Theanine, 5-HTP and B6 to promote a clear, calm mind.
Reishi: The Chill Pill (Without the Pill)

What it’s good for: Stress relief, immune support, and restful sleep.
How it’s used: Commonly found in tinctures or teas, often enjoyed before bed.
Local note: Companies like Om Mushrooms offer Oregon-made blends with reishi for that “exhale” moment at the end of a long day.
Turkey Tail: The Gut Guardian

What it’s good for: Supporting a balanced gut microbiome and immune health.
How it’s used: Capsules or teas—many mix it into smoothies for easy sipping.
Local roots: Wild turkey tail actually grows in our Oregon forests! Host Defense’s Turkey Tail Mushroom Mycelium products are crafted from these abundant mushrooms.
Cordyceps: The Energy Spark

What it’s good for: Endurance, stamina, and oxygen uptake (athletes love this one).
How it’s used: Often powdered and stirred into coffee or protein shakes.
Local angle: Pacific Northwest brands blend cordyceps into “performance” mushroom mixes for a natural energy lift.
Chaga: The Antioxidant Powerhouse

What it’s good for: Supporting skin health, reducing oxidative stress, and overall wellness.
How it’s used: Brewed like tea or taken as a tincture.
Local sip: Oregon herbal companies sometimes blend chaga with cacao for a cozy, antioxidant-rich drinking chocolate.
Local Brands We Love
We’re lucky to have some of the best mushroom supplement makers right here in the Pacific Northwest. A few you’ll find on our shelves:
- Host Defense (Olympia, WA): Founded by mycologist Paul Stamets, they’re a pioneer in mushroom wellness. Known for capsules, powders, and tinctures featuring Lion’s Mane, Reishi, Turkey Tail, and more.
- Om Mushrooms (Carlsbad, CA with PNW distribution): A go-to for powders that mix beautifully into smoothies, lattes, and baking.
- MycoFormulas (Portland, OR): Specializing in blends for immune defense, focus, and daily vitality.
How to Use Mushroom Supplements
Getting started doesn’t have to feel intimidating. Here are a few easy (and tasty) ways to bring them into your daily routine:
- Reishi Hot Cocoa: Stir a teaspoon of reishi powder into your favorite hot chocolate for a calming evening treat.
- Lion’s Mane Latte: Add Lion’s Mane powder to your morning coffee or oat milk latte for a smooth brain boost.
- Chaga Cacao: Brew chaga tea and mix it with warm milk, honey, and cinnamon for a cozy, antioxidant-packed sip.
- Cordyceps Smoothie: Toss cordyceps powder into a berry-banana smoothie for a natural energy kick pre-workout.
- Turkey Tail Tea: Steep turkey tail in hot water with a splash of lemon and ginger—it doubles as a soothing immune tonic.
- Feral Fungi: Tinctures and gummies that taste great and go down the hatch easy.
Things to Keep in Mind
- Start slow. If you’re new, try one mushroom type at a time so you know how your body responds.
- Check quality. Look for supplements made from the fruiting body (the mushroom itself), not just mycelium on grain. Local brands like Host Defense pride themselves on this.
- Talk with your doc. Mushrooms are powerful. They can interact with medications—especially blood thinners, immune therapies, or diabetes meds.
- They take time. Most folks notice benefits after consistent use for a few weeks, not overnight.
Getting Started with Mushroom Supplements
- Pick your goal. Want more focus? Try Lion’s Mane. Need calm? Reach for Reishi. Looking for stamina? Cordyceps might be your match.
- Choose your form. Capsules are easy, powders mix into smoothies, and tinctures are fast-absorbing.
- Keep it local. Support Pacific Northwest makers—our shelves are stocked with Oregon and Washington brands that know their fungi.
The Bottom Line
Mushroom supplements aren’t magic—but they’re pretty close. Whether you’re sipping a reishi latte, popping a Lion’s Mane capsule, or stirring cordyceps into your morning smoothie, you’re tapping into centuries of wisdom and a whole lot of local fungal know-how.
Next time you’re shopping, swing by our Whole Health section and check out the lineup of Pacific Northwest mushroom products. Our friendly staff will happily help you find the right one to get you started.
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